I don't understand how Deno is the game engine here, isn't it just the runtime for their chosen programming language? Is the CLR the "game engine" for games written in C#?
Anyway, this seems like a fun project and a neat use of Deno. I didn't know about the compile feature.
My second objection is that when I see a title of the form "using X as Y" (especially here, where the audience is technical) I expect the article content to be primarily about how X is useful for Y, and about the specific actions taken to make it fit for purpose. But this one seems to be largely about the consideration and rejection of other tools, and then the rest is basically just celebrating the experience of having made it work.
The main thing I learned about the game, outside of the screenshots and basic description, is that it uses a client-server model. Even though there's no clear reason why that would be necessary or even helpful beyond "it's written in TypeScript and that's what TypeScript devs are accustomed to". Certainly I can hardly fathom that any original implementation of SimCity too such an approach.
Anyway, this seems like a fun project and a neat use of Deno. I didn't know about the compile feature.